P110 INTRAVASCULAR LITHOTRIPSY FOR THE TREATMENT OF SEVERELY CALCIFIED LEFT MAIN CORONARY STENOSIS

Abstract Background Even if pilot studies have been conducted to validate Intravascular Lithotripsy, most challenging cases were excluded, including unprotected Left Main (LM) coronary stenosis. Methods We retrospectively enrolled patients treated with IVL in a real–world multicenter registry from 21 centers among Italy and Spain January 2020 November 2021. The primary safety endpoint was freedom major adverse cardiovascular events (cardiac death, target vessel revascularization, stent thrombosis) at 30 days. effectiveness procedural success (defined as delivery residual stenosis <20% without intra–procedural MACE). Secondary 6–months 12–months MACE rates. Results From total amount of 470 our registry, 41 underwent LM Most them males (78.0%). clinical presentation acute syndrome (ACS) 41.4% cases. Mechanical circulatory support necessary 4 (9.7%). before implantation planned 90% occurred 97.6%. patients. achieved 97.6% Interestingly, 6 months 12 months, no recorded. Conclusions lithotripsy for the treatment severely calcified seems be safe effective option very high rate low follow–up.